Pulmonary Neoplasia - Archives of Pathology & Laboratory Medicine

Pulmonary Neoplasia

By Archives of Pathology & Laboratory Medicine

  • Release Date - Published: 2008-07-01
  • Book Genre: Health & Fitness
  • Author: Archives of Pathology & Laboratory Medicine
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Pulmonary Neoplasia Archives of Pathology & Laboratory Medicine read online review & book description:

The diagnosis of pulmonary malignant neoplasia generally portends a poor prognosis. The facts are stark. Worldwide, lung cancer is expected to increase in prevalence during the 21st century. (1) Lung cancer is the leading cause of cancer death in both men and women in the United States. One in 10 cigarette smokers will develop lung cancer during his or her lifetime, with a decades-static overall 5-year survival rate for lung cancer in the United States of approximately 15%. (1-3) More people die of lung cancer than prostate, colon, and breast cancers combined. (4,5) Earlier detection of lung cancer is being promoted, and therapeutic response to epidermal growth factor receptor tyrosine kinase inhibitors gefitinib and erlotinib has been identified in a limited number of adenocarcinomas, generally in nonsmoking Asian women. (6-9) However, although molecular therapies show promise for the future, presently molecular therapy does not affect overall lung cancer prognosis. (10-12) Although rare, pleural diffuse malignant mesothelioma has increased in incidence worldwide during the last several decades and is rapidly increasing in incidence throughout Western Europe. (13-15) It is generally refractory to treatment, and overall survival is dismal, with a median of less than 12 months postdiagnosis. (13,16)

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