Therapeutic and Diagnostic Advances in the HAART Era (Essays) - Research Initiative/Treatment Action!

Therapeutic and Diagnostic Advances in the HAART Era (Essays)

By Research Initiative/Treatment Action!

  • Release Date - Published: 2005-06-22
  • Book Genre: Health & Fitness
  • Author: Research Initiative/Treatment Action!
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Therapeutic and Diagnostic Advances in the HAART Era (Essays) Research Initiative/Treatment Action! read online review & book description:

It has been almost 10 years since the approval of the first protease inhibitor, saquinavir (Invirase) in December 1995. Since that time, there have been great advances in treatment monitoring, treatment strategies, and overall knowledge about the pathogenesis of the disease, but we are still far from a cure and the virus continues to outsmart all the advances that have been made. Results from the first-generation protease inhibitor--saquinavir, ritonavir (Norvir), and indinavir (Crixivan)--combination studies were greeted with much excitement as they showed a profound effect on survival and ability to control virus replication. Starting in 1996, several studies and cohorts demonstrated dramatic decreases in mortality and opportunistic infections with the widespread availability of the protease inhibitors. The term "HAART" (highly active antiretroviral therapy) was first used around this time.

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